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Barrett's Oesophagus
Article Details

Last Updated
29th o March, 2008

The condition is named after Dr. Norman Barrett Australian-born surgeon who described the condition in 1957.

Barrett's Oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged. The damage is caused by stomach acid that leaks back into the oesophagus. This leakage of acid is more commonly known as Reflux.

The treatment
involves looking at the oesophagus with an endoscope and obtaining a sample of oesophagus tissue for examination (Oesophagoscopy with biopsy) may reveal Barrett's Oesophagus.

Treatment includes general measures to control gastro-oesophageal reflux, medications, photodynamic therapy (PDT), and surgery.
  •         Medications to relieve symptoms and control GORD include antacids, histamine H2 receptor blockers, proton pump inhibitors, cholinergic agents, and promotility agents.

  •         Surgery to remove a portion of the oesophagus may be recommended, if a biopsy shows the type of cellular changes called dysplasia.

  •         Photodynamic therapy (PDT) is a newly approved option that may avoid surgery. PDT involves the use of a special laser device, called an oesophageal balloon, along with a drug called Photofrin. Together, the laser balloon and medication lead to destruction of the abnormal cells lining the oesophagus, without affecting the normal tissue.


Source: Jenifer K. Lehrer, MD
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